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We postulated that combination of double mutation and elevat

 
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parent3cell
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PostPosted: Tue Jan 30, 2018 5:01 am    Post subject: We postulated that combination of double mutation and elevat Reply with quote

We postulated that combination of double mutation and elevated
Thus, maintaining a high rate of photosynthesis and biomass formation at elevated, non-physiological temperatures either by increasing the PSIIRC stability or enhancing the rate of D1 repair or both, represent major challenges in acclimatizing photosynthetic mesophiles to global warming. Although many studies have aimed at resolving the role of thylakoids’ fatty acid saturation in inducing thermotolerance to photosynthetic organisms, we have focused on proteins comprising the PSIIRC. Three major observations provided us with new clues for better understanding the strategy of PSIIRC adaptation Paclitaxel Microtubule inhibitor to elevated temperatures. First, as we previously showed, the temperature dependence of the first electron transfer rate in mesophiles and thermophiles follows Arrhenius kinetics until it levels off at which turned-out to be within the physiological temperature range of the examined mesophiles and thermophiles. Second, screening the amino acid sequences in the subunits of many photosynthetic thermophiles and mesophiles revealed consistent Pazopanib VEGFR/PDGFR inhibitor variations in two conserved sites within a motif at the protein center. More specifically in mesophiles are replaced by Cys and Ala in thermophiles. Third, single mutations at each of the aforementioned sites could increase the value in line with the observed values in thermophilic strains.
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